IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis

IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis (CIA). Neutralizing IL-23 after onset of CIA in rats has been shown to reduce paw volume, but the effect on synovial inflammation and the immunolo...

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Detalles Bibliográficos
Autores principales: Cornelissen, Ferry, Asmawidjaja, Patrick S., Mus, Adriana M. C., Corneth, Odilia, Kikly, Kristine, Lubberts, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585376/
https://www.ncbi.nlm.nih.gov/pubmed/23469022
http://dx.doi.org/10.1371/journal.pone.0057553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585376/
https://www.ncbi.nlm.nih.gov/pubmed/23469022
http://dx.doi.org/10.1371/journal.pone.0057553

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