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An Entropic Mechanism of Generating Selective Ion Binding in Macromolecules

Several mechanisms have been proposed to explain how ion channels and transporters distinguish between similar ions, a process crucial for maintaining proper cell function. Of these, three can be broadly classed as mechanisms involving specific positional constraints on the ion coordinating ligands...

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Detalles Bibliográficos
Autores principales: Thomas, Michael, Jayatilaka, Dylan, Corry, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585399/
https://www.ncbi.nlm.nih.gov/pubmed/23468604
http://dx.doi.org/10.1371/journal.pcbi.1002914