Enhancing Human Spermine Synthase Activity by Engineered Mutations

Spermine synthase (SMS) is an enzyme which function is to convert spermidine into spermine. It was shown that gene defects resulting in amino acid changes of the wild type SMS cause Snyder-Robinson syndrome, which is a mild-to-moderate mental disability associated with osteoporosis, facial asymmetry...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Zheng, Yueli, Petukh, Margo, Pegg, Anthony, Ikeguchi, Yoshihiko, Alexov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585406/
https://www.ncbi.nlm.nih.gov/pubmed/23468611
http://dx.doi.org/10.1371/journal.pcbi.1002924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585406/
https://www.ncbi.nlm.nih.gov/pubmed/23468611
http://dx.doi.org/10.1371/journal.pcbi.1002924

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