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Regulation of Herpes Simplex Virus gB-Induced Cell-Cell Fusion by Mutant Forms of gH/gL in the Absence of gD and Cellular Receptors

Herpesvirus entry requires the viral glycoprotein triad of gB and gH/gL to carry out fusion between the virion envelope and a cellular membrane in order to release the nucleocapsid into the target cell. Herpes simplex virus (HSV) also requires glycoprotein gD to initiate the fusion cascade by bindin...

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Detalles Bibliográficos
Autores principales: Atanasiu, Doina, Cairns, Tina M., Whitbeck, J. Charles, Saw, Wan Ting, Rao, Samhita, Eisenberg, Roselyn J., Cohen, Gary H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585445/
https://www.ncbi.nlm.nih.gov/pubmed/23443004
http://dx.doi.org/10.1128/mBio.00046-13