Cargando…

A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

The maintenance of pluripotency in mouse embryonic stem cells (mESCs) relies on the activity of a transcriptional network that is fuelled by the activity of three transcription factors (Nanog, Oct4 and Sox2) and balanced by the repressive activity of Tcf3. Extracellular signals modulate the activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Faunes, Fernando, Hayward, Penelope, Descalzo, Silvia Muñoz, Chatterjee, Sujash S., Balayo, Tina, Trott, Jamie, Christoforou, Andrew, Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Dasgupta, Ramanuj, Arias, Alfonso Martinez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585656/
https://www.ncbi.nlm.nih.gov/pubmed/23444350
http://dx.doi.org/10.1242/dev.085654