Cargando…
A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells
The maintenance of pluripotency in mouse embryonic stem cells (mESCs) relies on the activity of a transcriptional network that is fuelled by the activity of three transcription factors (Nanog, Oct4 and Sox2) and balanced by the repressive activity of Tcf3. Extracellular signals modulate the activity...
Autores principales: | Faunes, Fernando, Hayward, Penelope, Descalzo, Silvia Muñoz, Chatterjee, Sujash S., Balayo, Tina, Trott, Jamie, Christoforou, Andrew, Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Dasgupta, Ramanuj, Arias, Alfonso Martinez |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585656/ https://www.ncbi.nlm.nih.gov/pubmed/23444350 http://dx.doi.org/10.1242/dev.085654 |
Ejemplares similares
-
A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells
por: Muñoz Descalzo, Silvia, et al.
Publicado: (2013) -
Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells
por: Turner, David A., et al.
Publicado: (2014) -
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
por: Le Bin, Gloryn Chia, et al.
Publicado: (2014) -
Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells
por: van den Brink, Susanne C., et al.
Publicado: (2014) -
Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development
por: Vogt, Edgar J., et al.
Publicado: (2012)