Cargando…

Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis

Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator...

Descripción completa

Detalles Bibliográficos
Autores principales: McNamara, Colleen R., Ahuja, Ruchita, Osafo-Addo, Awo D., Barrows, Douglas, Kettenbach, Arminja, Skidan, Igor, Teng, Xin, Cuny, Gregory D., Gerber, Scott, Degterev, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585731/
https://www.ncbi.nlm.nih.gov/pubmed/23469174
http://dx.doi.org/10.1371/journal.pone.0056576