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Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585731/ https://www.ncbi.nlm.nih.gov/pubmed/23469174 http://dx.doi.org/10.1371/journal.pone.0056576 |