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Food Effects on the Pharmacokinetics of Doxylamine Hydrogen Succinate 25 mg Film-Coated Tablets: A Single-Dose, Randomized, Two-Period Crossover Study in Healthy Volunteers

BACKGROUND: Doxylamine succinate, an ethanolamine-based antihistamine, is used in the short-term management of insomnia because of its sedative effects. The data available on the pharmacokinetic profile of doxylamine in humans are limited, notwithstanding that this drug has been marketed in European...

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Detalles Bibliográficos
Autores principales: Videla, Sebastián, Lahjou, Mounia, Guibord, Pascal, Xu, Zhengguo, Tolrà, Carles, Encina, Gregorio, Sicard, Eric, Sans, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585842/
https://www.ncbi.nlm.nih.gov/pubmed/23230999
http://dx.doi.org/10.2165/11641640-000000000-00000