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Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway

Mesothelin, a secreted protein, is overexpressed in some cancers, including pancreatic cancer. Rescent studies have shown that overexpression of mesothelin significantly increased tumor cell proliferation, and downregulation of mesothelin inhibited cell proliferation in pancreatic cancer cells, but...

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Detalles Bibliográficos
Autores principales: Zheng, Chunning, Jia, Wei, Tang, Yong, Zhao, HuiLiang, Jiang, Yingsheng, Sun, Shaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585882/
https://www.ncbi.nlm.nih.gov/pubmed/23034174
http://dx.doi.org/10.1186/1756-9966-31-84