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Age and CD161 Expression Contribute to Inter-Individual Variation in Interleukin-23 Response in CD8+ Memory Human T Cells

The interleukin-23 (IL-23) pathway plays a critical role in the pathogenesis of multiple chronic inflammatory disorders, however, inter-individual variability in IL-23-induced signal transduction in circulating human lymphocytes has not been well-defined. In this study, we observed marked, reproduci...

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Detalles Bibliográficos
Autores principales: Shen, Hui, Zhang, Wei, Abraham, Clara, Cho, Judy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585933/
https://www.ncbi.nlm.nih.gov/pubmed/23469228
http://dx.doi.org/10.1371/journal.pone.0057746