A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

The cholesterol biosynthesis pathway has recently been shown to play an important role in the innate immune response to viral infection with host protection occurring through a coordinate down regulation of the enzymes catalysing each metabolic step. In contrast, statin based drugs, which form the p...

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Detalles Bibliográficos
Autores principales: Watterson, Steven, Guerriero, Maria Luisa, Blanc, Mathieu, Mazein, Alexander, Loewe, Laurence, Robertson, Kevin A., Gibbs, Holly, Shui, Guanghou, Wenk, Markus R., Hillston, Jane, Ghazal, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585962/
https://www.ncbi.nlm.nih.gov/pubmed/22664637
http://dx.doi.org/10.1016/j.biochi.2012.05.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585962/
https://www.ncbi.nlm.nih.gov/pubmed/22664637
http://dx.doi.org/10.1016/j.biochi.2012.05.024

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