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Bioequivalence and Tolerability Assessment of a Novel Intravenous Ciclosporin Lipid Emulsion Compared to Branded Ciclosporin in Cremophor(®) EL

BACKGROUND: Ciclosporin is used as an immunosuppressant in current clinical practice but recent research implies novel indications for the drug, such as neuro- and cardioprotection. The intravenous formulation currently on the market, Sandimmune(®) Injection (Sandimmune(®)), uses Cremophor(®) EL as...

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Detalles Bibliográficos
Autores principales: Ehinger, Karl Henrik Johannes, Hansson, Magnus Joakim, Sjövall, Fredrik, Elmér, Eskil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586182/
https://www.ncbi.nlm.nih.gov/pubmed/23179472
http://dx.doi.org/10.1007/s40261-012-0029-x