Cargando…

Bioequivalence and Tolerability Assessment of a Novel Intravenous Ciclosporin Lipid Emulsion Compared to Branded Ciclosporin in Cremophor(®) EL

BACKGROUND: Ciclosporin is used as an immunosuppressant in current clinical practice but recent research implies novel indications for the drug, such as neuro- and cardioprotection. The intravenous formulation currently on the market, Sandimmune(®) Injection (Sandimmune(®)), uses Cremophor(®) EL as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ehinger, Karl Henrik Johannes, Hansson, Magnus Joakim, Sjövall, Fredrik, Elmér, Eskil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing AG 2012
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586182/ https://www.ncbi.nlm.nih.gov/pubmed/23179472 http://dx.doi.org/10.1007/s40261-012-0029-x

Ejemplares similares

Erratum to: Bioequivalence and Tolerability Assessment of a Novel Intravenous Ciclosporin Lipid Emulsion Compared to Branded Ciclosporin in Cremophor(®) EL
por: Ehinger, Karl Henrik Johannes, et al.
Publicado: (2013)

Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients
por: Kelsen, Jesper, et al.
Publicado: (2019)

Ciclosporin 10 years on: indications and efficacy
por: Forsythe, Peter, et al.
Publicado: (2014)

Ciclosporin: Various toxicities: case report
Publicado: (2022)

Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): a study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study
por: Ederoth, Per, et al.
Publicado: (2016)

Ciclosporin in canine dermatology: a decade of comfort
por: DeBoer, Douglas J.
Publicado: (2014)

Acitretin/ciclosporin: Treatment failure : case report
Publicado: (2021)

Ciclosporin/prednisone: Visceral leishmaniasis: case report
Publicado: (2022)

Elevation of blood ciclosporin levels by voriconazole leading to leukoencephalopathy
por: Caihong, Qu, et al.
Publicado: (2013)

Ciclosporin/methylprednisolone: COVID-19 infection: case report
Publicado: (2022)

Ciclosporin/methylprednisolone: COVID-19 infection: case report
Publicado: (2022)

Clinical Outcomes of Topical 0.1% Ciclosporin Cationic Emulsion Used on Label in Children with Vernal Keratoconjunctivitis
por: Giannaccare, Giuseppe, et al.
Publicado: (2023)

Repeated oral dose tolerance in dogs treated concomitantly with ciclosporin and oclacitinib for three weeks
por: Panteri, Alessandro, et al.
Publicado: (2015)

Explaining variability in ciclosporin exposure in adult kidney transplant recipients
por: Press, Rogier R., et al.
Publicado: (2010)

Glucocorticosteroids and ciclosporin do not significantly impact canine cutaneous microbiota
por: Widmer, Giovanni, et al.
Publicado: (2018)

Ciclosporin/everolimus/prednisone: COVID-19 pneumonia: case report
Publicado: (2021)

Ciclosporin/rituximab: Lack of efficacy and COVID-19: case report
Publicado: (2020)

Antithymocyte-globulin/ciclosporin/eltrombopag: Lack of efficacy: case report
Publicado: (2022)

Ciclosporin/tozinameran: Behcet's disease and hepatic damage: 2 case reports
Publicado: (2022)

Ciclosporin/mycophenolate-mofetil/steroids: COVID-19 pneumonia: case report
Publicado: (2021)

Case Report: Ciclosporin A for Refractory Multisystem Inflammatory Syndrome in Children
por: Suzuki, Takayuki, et al.
Publicado: (2022)

Bioequivalence study between two formulations of ciclosporin A (Cyclavance® oral solution and Atopica® soft capsules) following a single oral administration to dogs
por: Navarro, C., et al.
Publicado: (2016)

Endomyocardial, intralymphocyte, and whole blood concentrations of ciclosporin A in heart transplant recipients
por: Robertsen, Ida, et al.
Publicado: (2013)

Ciclosporin/methylprednisolone/tocilizumab: COVID-19 pneumonia, leukopenia and neutropenia: case report
Publicado: (2020)

AZD-1222/ciclosporin: Reactivation of recurrent herpes zoster: 3 case reports
Publicado: (2021)

Mycophenolate mofetil/ciclosporin/prednisolone: COVID-19 infection: 2 case reports
Publicado: (2021)

Ciclosporin/prednisolone: COVID-19 infection and Klebsiella pneumoniae septicaemia: case report
Publicado: (2022)

Ciclosporin/mycophenolate mofetil: Lack of efficacy and off-label use: case report
Publicado: (2022)

Acitretin/ciclosporin: Lack of efficacy during treatment of palmar psoriasis: case report
Publicado: (2022)

Ciclosporin/tozinameran: Vaccination failure and poor serological response: 2 case reports
Publicado: (2021)

Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production
por: Piel, Sarah, et al.
Publicado: (2018)

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose
por: Piel, Sarah, et al.
Publicado: (2020)

Nasal Planum Vasculopathy in a Scottish Terrier Dog Treated with Ciclosporin and Endonasal Stents
por: Sartori, Roberta, et al.
Publicado: (2018)

Comparative study to evaluate the voluntary acceptance of two liquid oral formulations of ciclosporin in dogs
por: Kammanadiminti, Srinivas J., et al.
Publicado: (2018)

Simvastatin-induced myoglobinuric acute kidney injury following ciclosporin treatment for alopecia universalis
por: Teutonico, Annalisa, et al.
Publicado: (2010)

Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction
por: Cormack, Suzanne, et al.
Publicado: (2020)

Ciclosporin/steroids: Pandemic (H1N1)-associated ARDS: case report
Publicado: (2013)

Ciclosporin/cyclophosphamide/mycophenolate mofetil: Bacterial, viral and fungal infections: 71 case reports
Publicado: (2019)

Postconditioning by Delayed Administration of Ciclosporin A: Implication for Donation after Circulatory Death (DCD)
por: Ferrera, René, et al.
Publicado: (2022)

Voluntary acceptance and consumption of two oral ciclosporin formulations in dogs: two randomised, controlled studies
por: Navarro, Christelle, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3n9hl7hjtadhc4484gtb8rfrur