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Differential Effects of the CRF-R1 Antagonist GSK876008 on Fear-Potentiated, Light- and CRF-Enhanced Startle Suggest Preferential Involvement in Sustained versus Phasic Threat Responses

The amplitude of the acoustic startle response is increased when elicited in the presence of brief cues that predict shock (fear-potentiated startle) and also when elicited during sustained exposure to bright light (light-enhanced startle). Although both effects are thought to reflect fear or anxiet...

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Detalles Bibliográficos
Autores principales: Walker, D., Yang, Y., Ratti, E., Corsi, M., Trist, D., Davis, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586210/
https://www.ncbi.nlm.nih.gov/pubmed/19078950
http://dx.doi.org/10.1038/npp.2008.210