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MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting αvβ3-mediated SDF-1/CXCR4 signaling

The majority of glioblastoma multiforme (GBM) tumors recur after radiation (IR) treatment due to increased angiogenesis and IR-induced signaling events in endothelial cells (ECs) that are involved in tumor neovascularization; however, these signaling events have yet to be well characterized. In the...

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Detalles Bibliográficos
Autores principales: MADDIRELA, DILIP RAJASEKHAR, KESANAKURTI, DIVYA, GUJRATI, MEENA, RAO, JASTI S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586295/
https://www.ncbi.nlm.nih.gov/pubmed/23381805
http://dx.doi.org/10.3892/ijo.2013.1806