E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors

BACKGROUND: The tumor suppressor gene E-cadherin gene is frequently silenced in chronic lymphocytic leukemia (CLL) cells and results in wnt-pathway activation. We analyzed the role of histone epigenetic modifications in E-cadherin gene silencing. METHODS: CLL specimens were treated with histone deac...

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Detalles Bibliográficos
Autores principales: Jordaan, Gwen, Liao, Wei, Sharma, Sanjai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586366/
https://www.ncbi.nlm.nih.gov/pubmed/23432814
http://dx.doi.org/10.1186/1471-2407-13-88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586366/
https://www.ncbi.nlm.nih.gov/pubmed/23432814
http://dx.doi.org/10.1186/1471-2407-13-88

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