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E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors

BACKGROUND: The tumor suppressor gene E-cadherin gene is frequently silenced in chronic lymphocytic leukemia (CLL) cells and results in wnt-pathway activation. We analyzed the role of histone epigenetic modifications in E-cadherin gene silencing. METHODS: CLL specimens were treated with histone deac...

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Detalles Bibliográficos
Autores principales:	Jordaan, Gwen, Liao, Wei, Sharma, Sanjai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586366/ https://www.ncbi.nlm.nih.gov/pubmed/23432814 http://dx.doi.org/10.1186/1471-2407-13-88

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