Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study

Glucokinase (GK) is the predominant hexokinase that acts as glucose sensor and catalyses the formation of Glucose-6-phosphate. The mutations in GK gene influence the affinity for glucose and lead to altered glucose levels in blood causing maturity onset diabetes of the young type 2 (MODY2) condition...

Descripción completa

Detalles Bibliográficos
Autores principales: Yellapu, Nanda Kumar, Kandlapalli, Kalpana, Valasani, Koteswara Rao, Sarma, P. V. G. K., Matcha, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586473/
https://www.ncbi.nlm.nih.gov/pubmed/23476789
http://dx.doi.org/10.1155/2013/264793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586473/
https://www.ncbi.nlm.nih.gov/pubmed/23476789
http://dx.doi.org/10.1155/2013/264793

Ejemplares similares