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Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone. Mortality is determined by the presence of metastatic disease, but little is known regarding the biochemical events that drive metastases. Two murine OS cell lines, K7M2 and K12, are related but differ significantly in their metastatic...

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Detalles Bibliográficos
Autores principales: Mu, Xiaodong, Isaac, Christian, Schott, Trevor, Huard, Johnny, Weiss, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586506/
https://www.ncbi.nlm.nih.gov/pubmed/23476113
http://dx.doi.org/10.1155/2013/480713