Cargando…
Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells
Osteosarcoma (OS) is the most common primary malignancy of bone. Mortality is determined by the presence of metastatic disease, but little is known regarding the biochemical events that drive metastases. Two murine OS cell lines, K7M2 and K12, are related but differ significantly in their metastatic...
Autores principales: | Mu, Xiaodong, Isaac, Christian, Schott, Trevor, Huard, Johnny, Weiss, Kurt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586506/ https://www.ncbi.nlm.nih.gov/pubmed/23476113 http://dx.doi.org/10.1155/2013/480713 |
Ejemplares similares
-
Notch Signaling is Associated with ALDH Activity and an Aggressive Metastatic Phenotype in Murine Osteosarcoma Cells
por: Mu, Xiaodong, et al.
Publicado: (2013) -
Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells
por: Mu, Xiaodong, et al.
Publicado: (2015) -
Notch Signaling Mediates Skeletal Muscle Atrophy in Cancer Cachexia Caused by Osteosarcoma
por: Mu, Xiaodong, et al.
Publicado: (2016) -
The HDAC Inhibitor Vorinostat Diminishes the In Vitro Metastatic Behavior of Osteosarcoma Cells
por: Mu, Xiaodong, et al.
Publicado: (2015) -
Rapamycin for aging stem cells
por: Hambright, William S., et al.
Publicado: (2020)