Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients

Introduction. Familial adenomatous polyposis (FAP) patients have a germline mutation in the adenomatous polyposis coli (APC) gene. The APC protein interacts with beta-catenin, resulting in the activation of the Wnt signalling pathway. This results in alterations in cell proliferation and apoptosis....

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Detalles Bibliográficos
Autores principales: Wang, Jayson, El-Masry, Nabil, Talbot, Ian, Tomlinson, Ian, Alison, Malcolm R., El-Bahrawy, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586510/
https://www.ncbi.nlm.nih.gov/pubmed/23476634
http://dx.doi.org/10.1155/2013/107534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586510/
https://www.ncbi.nlm.nih.gov/pubmed/23476634
http://dx.doi.org/10.1155/2013/107534

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