PKM2, a Central Point of Regulation in Cancer Metabolism

Aerobic glycolysis is the dominant metabolic pathway utilized by cancer cells, owing to its ability to divert glucose metabolites from ATP production towards the synthesis of cellular building blocks (nucleotides, amino acids, and lipids) to meet the demands of proliferation. The M2 isoform of pyruv...

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Detalles Bibliográficos
Autores principales: Wong, Nicholas, De Melo, Jason, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586519/
https://www.ncbi.nlm.nih.gov/pubmed/23476652
http://dx.doi.org/10.1155/2013/242513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586519/
https://www.ncbi.nlm.nih.gov/pubmed/23476652
http://dx.doi.org/10.1155/2013/242513

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