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Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility
Variation in polyglutamine repeat number in the androgen receptor (AR CAGn) is negatively correlated with the transcription of androgen-responsive genes and is associated with susceptibility to an extensive list of human disease. Only a small portion of the heritability for many of these diseases is...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586616/ https://www.ncbi.nlm.nih.gov/pubmed/23467468 http://dx.doi.org/10.1111/j.1752-4571.2012.00275.x |