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Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility

Variation in polyglutamine repeat number in the androgen receptor (AR CAGn) is negatively correlated with the transcription of androgen-responsive genes and is associated with susceptibility to an extensive list of human disease. Only a small portion of the heritability for many of these diseases is...

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Detalles Bibliográficos
Autores principales: Ryan, Calen P, Crespi, Bernard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586616/
https://www.ncbi.nlm.nih.gov/pubmed/23467468
http://dx.doi.org/10.1111/j.1752-4571.2012.00275.x

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