Cargando…

Efficient Sleeping Beauty DNA Transposition From DNA Minicircles

DNA transposon-based vectors have emerged as new potential delivery tools in therapeutic gene transfer. Such vectors are now showing promise in hematopoietic stem cells and primary human T cells, and clinical trials with transposon-engineered cells are on the way. However, the use of plasmid DNA as...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Nynne, Cai, Yujia, Bak, Rasmus O, Jakobsen, Martin R, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586802/
https://www.ncbi.nlm.nih.gov/pubmed/23443502
http://dx.doi.org/10.1038/mtna.2013.1