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Mass Spectrometry Reveals Changes in MHC I Antigen Presentation After Lentivector Expression of a Gene Regulation System

The rapamycin-inducible gene regulation system was designed to minimize immune reactions in man and may thus be suited for gene therapy. We assessed whether this system indeed induces no immune responses. The protein components of the regulation system were produced in the human cell lines HEK 293T,...

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Detalles Bibliográficos
Autores principales: Vogel, Roland, Al-Daccak, Reem, Drews, Oliver, Alonzeau, Jessy, Mester, Gabor, Charron, Dominique, Stevanovic, Stefan, Mallet, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586803/
https://www.ncbi.nlm.nih.gov/pubmed/23403517
http://dx.doi.org/10.1038/mtna.2013.3