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Mass Spectrometry Reveals Changes in MHC I Antigen Presentation After Lentivector Expression of a Gene Regulation System
The rapamycin-inducible gene regulation system was designed to minimize immune reactions in man and may thus be suited for gene therapy. We assessed whether this system indeed induces no immune responses. The protein components of the regulation system were produced in the human cell lines HEK 293T,...
Autores principales: | Vogel, Roland, Al-Daccak, Reem, Drews, Oliver, Alonzeau, Jessy, Mester, Gabor, Charron, Dominique, Stevanovic, Stefan, Mallet, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586803/ https://www.ncbi.nlm.nih.gov/pubmed/23403517 http://dx.doi.org/10.1038/mtna.2013.3 |
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