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Isoniazid MIC and KatG Gene Mutations among Mycobacterium tuberculosis Isolates in Northwest of Iran

OBJECTIVE(S): Isoniazid (INH) is one of the main first line drugs used in treatment of tuberculosis and development of resistance against this compound can result in serious problems in treatment procedures. Resistance to INH is mediated mainly by mutation in KatG gene that is coded for the catalase...

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Detalles Bibliográficos
Autores principales: Moaddab, Seed Reza, Farajnia, Safar, Kardan, Davood, Zamanlou, Sajad, Alikhani, Mohammad Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586854/
https://www.ncbi.nlm.nih.gov/pubmed/23493326