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Differential Metabolic Effects of Novel Cilostamide Analogs, Methyl Carbostiryl Derivatives, on Mouse and Hyperglycemic Rat

Objective(s):PDE3 has a functional role in insulin secretion and action. We investigated the metabolic effects of new synthetic PDE3 inhibitors (mc1, mc2, mc5 and mc6), on mice and hyperglycemic rat. Materials and Methods:The test compound or solvent was injected subcutaneously to mice, for 7 days....

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Detalles Bibliográficos
Autores principales: Hosseini, Azar, Shafiee-Nick, Reza, Pour Ali Behzad, Nasser, Sadeghian, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586914/
https://www.ncbi.nlm.nih.gov/pubmed/23493150