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Comparison of co-expression measures: mutual information, correlation, and model based indices

BACKGROUND: Co-expression measures are often used to define networks among genes. Mutual information (MI) is often used as a generalized correlation measure. It is not clear how much MI adds beyond standard (robust) correlation measures or regression model based association measures. Further, it is...

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Detalles Bibliográficos
Autores principales: Song, Lin, Langfelder, Peter, Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586947/
https://www.ncbi.nlm.nih.gov/pubmed/23217028
http://dx.doi.org/10.1186/1471-2105-13-328