Effects of Dual Targeting of Tumor Cells and Stroma in Human Glioblastoma Xenografts with a Tyrosine Kinase Inhibitor against c-MET and VEGFR2

Anti-angiogenic treatment of glioblastoma with Vascular Endothelial Growth Factor (VEGF)- or VEGF Receptor 2 (VEGFR2) inhibitors normalizes tumor vessels, resulting in a profound radiologic response and improved quality of life. This approach however does not halt tumor progression by diffuse infilt...

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Detalles Bibliográficos
Autores principales: Navis, Anna C., Bourgonje, Annika, Wesseling, Pieter, Wright, Alan, Hendriks, Wiljan, Verrijp, Kiek, van der Laak, Jeroen A. W. M., Heerschap, Arend, Leenders, William P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587584/
https://www.ncbi.nlm.nih.gov/pubmed/23484006
http://dx.doi.org/10.1371/journal.pone.0058262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587584/
https://www.ncbi.nlm.nih.gov/pubmed/23484006
http://dx.doi.org/10.1371/journal.pone.0058262

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