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Impaired Acetylcholine-Induced Endothelium-Dependent Aortic Relaxation by Caveolin-1 in Angiotensin II-Infused Apolipoprotein-E (ApoE(−/−)) Knockout Mice

OBJECTIVE: The angiotensin II (AngII)-infused apolipoprotein E-deficient (ApoE(−/−)) mouse model is widely used to study atherosclerosis and abdominal aortic aneurysm. An increase in blood pressure has been reported in this model however the underlying mechanism has not been fully explored. In this...

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Detalles Bibliográficos
Autores principales: Seto, Sai Wang, Krishna, Smriti M., Yu, Hongyou, Liu, David, Khosla, Surabhi, Golledge, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587590/
https://www.ncbi.nlm.nih.gov/pubmed/23469284
http://dx.doi.org/10.1371/journal.pone.0058481