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Impaired Acetylcholine-Induced Endothelium-Dependent Aortic Relaxation by Caveolin-1 in Angiotensin II-Infused Apolipoprotein-E (ApoE(−/−)) Knockout Mice
OBJECTIVE: The angiotensin II (AngII)-infused apolipoprotein E-deficient (ApoE(−/−)) mouse model is widely used to study atherosclerosis and abdominal aortic aneurysm. An increase in blood pressure has been reported in this model however the underlying mechanism has not been fully explored. In this...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587590/ https://www.ncbi.nlm.nih.gov/pubmed/23469284 http://dx.doi.org/10.1371/journal.pone.0058481 |