Structural Characterization of a Recombinant Fusion Protein by Instrumental Analysis and Molecular Modeling

Conbercept is a genetically engineered homodimeric protein for the treatment of wet age-related macular degeneration (wet AMD) that functions by blocking VEGF-family proteins. Its huge, highly variable architecture makes characterization and development of a functional assay difficult. In this study...

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Detalles Bibliográficos
Autores principales: Wu, Zhigang, Zhou, Peng, Li, Xiaoxin, Wang, Hui, Luo, Delun, Qiao, Huaiyao, Ke, Xiao, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587646/
https://www.ncbi.nlm.nih.gov/pubmed/23469213
http://dx.doi.org/10.1371/journal.pone.0057642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587646/
https://www.ncbi.nlm.nih.gov/pubmed/23469213
http://dx.doi.org/10.1371/journal.pone.0057642

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