Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress

Parkinson’s disease (PD) is one of the most common age-related neurodegenerative diseases. This pathology causes a significant loss of dopaminergic neurons in the Substantia Nigra. Several reports have claimed a role of defective nuclear and mitochondrial DNA repair pathways in PD etiology, in parti...

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Detalles Bibliográficos
Autores principales: Ciccone, Sarah, Maiani, Emiliano, Bellusci, Giovanna, Diederich, Marc, Gonfloni, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587993/
https://www.ncbi.nlm.nih.gov/pubmed/23348931
http://dx.doi.org/10.3390/ijms14022388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587993/
https://www.ncbi.nlm.nih.gov/pubmed/23348931
http://dx.doi.org/10.3390/ijms14022388

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