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Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress
Parkinson’s disease (PD) is one of the most common age-related neurodegenerative diseases. This pathology causes a significant loss of dopaminergic neurons in the Substantia Nigra. Several reports have claimed a role of defective nuclear and mitochondrial DNA repair pathways in PD etiology, in parti...
Autores principales: | Ciccone, Sarah, Maiani, Emiliano, Bellusci, Giovanna, Diederich, Marc, Gonfloni, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587993/ https://www.ncbi.nlm.nih.gov/pubmed/23348931 http://dx.doi.org/10.3390/ijms14022388 |
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