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The Yin-Yang of DNA Damage Response: Roles in Tumorigenesis and Cellular Senescence
Senescent cells are relatively stable, lacking proliferation capacity yet retaining metabolic activity. In contrast, cancer cells are rather invasive and devastating, with uncontrolled proliferative capacity and resistance to cell death signals. Although tumorigenesis and cellular senescence are see...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587995/ https://www.ncbi.nlm.nih.gov/pubmed/23354477 http://dx.doi.org/10.3390/ijms14022431 |