Structural Characterization of an LPA(1) Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint

G protein-coupled receptor (GPCR) structures are of interest as a means to understand biological signal transduction and as tools for therapeutic discovery. The growing number of GPCR crystal structures demonstrates that the extracellular loops (EL) connecting the membrane-spanning helices show trem...

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Detalles Bibliográficos
Autores principales: Young, John K., Clayton, Benjamin T., Kikonyogo, Alexandra, Pham, Truc-Chi T., Parrill, Abby L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588015/
https://www.ncbi.nlm.nih.gov/pubmed/23434648
http://dx.doi.org/10.3390/ijms14022788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588015/
https://www.ncbi.nlm.nih.gov/pubmed/23434648
http://dx.doi.org/10.3390/ijms14022788

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