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Structural Characterization of an LPA(1) Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint
G protein-coupled receptor (GPCR) structures are of interest as a means to understand biological signal transduction and as tools for therapeutic discovery. The growing number of GPCR crystal structures demonstrates that the extracellular loops (EL) connecting the membrane-spanning helices show trem...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588015/ https://www.ncbi.nlm.nih.gov/pubmed/23434648 http://dx.doi.org/10.3390/ijms14022788 |