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In Vitro and in Vivo Evaluation of Lactoferrin-Conjugated Liposomes as a Novel Carrier to Improve the Brain Delivery

In this study, lactoferrin-conjugated PEGylated liposomes (PL), a potential drug carrier for brain delivery, was loaded with radioisotope complex, (99m)Tc labeled N,N-bis(2-mercaptoethyl)-N′,N′-diethylethylenediamine ((99m)Tc-BMEDA) for in vitro and in vivo evaluations. The hydrophilicity of liposom...

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Detalles Bibliográficos
Autores principales: Huang, Feng-Yun J., Chen, Wan-Jou, Lee, Wan-Yu, Lo, Su-Tang, Lee, Te-Wei, Lo, Jem-Mau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588019/
https://www.ncbi.nlm.nih.gov/pubmed/23434652
http://dx.doi.org/10.3390/ijms14022862