Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN

To better understand the molecular mechanisms of paclitaxel resistance in ovarian carcinoma, we evaluated the expression of miRNAs using miRNA microarray between human ovarian carcinoma SKOV3 cells and paclitaxel resistant SKOV3-TR30 cells. Results showed that 69 miRNAs were upregulated while 102 mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shuang, Ting, Shi, Chunxue, Chang, Shuang, Wang, Min, Bai, Cui Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588071/
https://www.ncbi.nlm.nih.gov/pubmed/23396109
http://dx.doi.org/10.3390/ijms14023802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588071/
https://www.ncbi.nlm.nih.gov/pubmed/23396109
http://dx.doi.org/10.3390/ijms14023802

Ejemplares similares