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Phenotypic Identification of the Redox Dye Methylene Blue as an Antagonist of Heat Shock Response Gene Expression in Metastatic Melanoma Cells

Repurposing approved and abandoned non-oncological drugs is an alternative developmental strategy for the identification of anticancer therapeutics that has recently attracted considerable attention. Due to the essential role of the cellular heat shock response in cytoprotection through the maintena...

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Detalles Bibliográficos
Autores principales: Davis, Angela L., Cabello, Christopher M., Qiao, Shuxi, Azimian, Sara, Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588094/
https://www.ncbi.nlm.nih.gov/pubmed/23429201
http://dx.doi.org/10.3390/ijms14024185