Cyclic Stretch Induces Inducible Nitric Oxide Synthase and Soluble Guanylate Cyclase in Pulmonary Artery Smooth Muscle Cells

In the pulmonary vasculature, mechanical forces such as cyclic stretch induce changes in vascular signaling, tone and remodeling. Nitric oxide is a potent regulator of soluble guanylate cyclase (sGC), which drives cGMP production, causing vasorelaxation. Pulmonary artery smooth muscle cells (PASMCs)...

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Detalles Bibliográficos
Autores principales: Shah, Monica R., Wedgwood, Stephen, Czech, Lyubov, Kim, Gina A., Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H., Farrow, Kathryn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588102/
https://www.ncbi.nlm.nih.gov/pubmed/23429274
http://dx.doi.org/10.3390/ijms14024334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588102/
https://www.ncbi.nlm.nih.gov/pubmed/23429274
http://dx.doi.org/10.3390/ijms14024334

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