Deciphering Signatures of Mutational Processes Operative in Human Cancer

The genome of a cancer cell carries somatic mutations that are the cumulative consequences of the DNA damage and repair processes operative during the cellular lineage between the fertilized egg and the cancer cell. Remarkably, these mutational processes are poorly characterized. Global sequencing i...

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Detalles Bibliográficos
Autores principales: Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Campbell, Peter J., Stratton, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588146/
https://www.ncbi.nlm.nih.gov/pubmed/23318258
http://dx.doi.org/10.1016/j.celrep.2012.12.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588146/
https://www.ncbi.nlm.nih.gov/pubmed/23318258
http://dx.doi.org/10.1016/j.celrep.2012.12.008

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