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Properties of cell death models calibrated and compared using Bayesian approaches

Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameters (initial protein concentrations and rate constants) for m...

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Detalles Bibliográficos
Autores principales: Eydgahi, Hoda, Chen, William W, Muhlich, Jeremy L, Vitkup, Dennis, Tsitsiklis, John N, Sorger, Peter K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588908/
https://www.ncbi.nlm.nih.gov/pubmed/23385484
http://dx.doi.org/10.1038/msb.2012.69