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The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation

Bronchodilators are a standard medicine for treating airway obstructive diseases, and β2 adrenergic receptor agonists have been the most commonly used bronchodilators since their discovery. Strikingly, activation of G-protein-coupled bitter taste receptors (TAS2Rs) in airway smooth muscle (ASM) caus...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng-Hai, Lifshitz, Lawrence M., Uy, Karl F., Ikebe, Mitsuo, Fogarty, Kevin E., ZhuGe, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589262/
https://www.ncbi.nlm.nih.gov/pubmed/23472053
http://dx.doi.org/10.1371/journal.pbio.1001501