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hTERT Extends the Life of Human Fibroblasts without Compromising Type I Interferon Signaling

Primary cells are often used to study viral replication and host-virus interactions as their antiviral pathways have not been altered or inactivated; however, their use is restricted by their short lifespan. Conventional methods to extend the life of primary cultures typically utilize viral oncogene...

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Detalles Bibliográficos
Autores principales: Smith, Miles C., Goddard, Erica T., Perusina Lanfranca, Mirna, Davido, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589264/
https://www.ncbi.nlm.nih.gov/pubmed/23472163
http://dx.doi.org/10.1371/journal.pone.0058233