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Abrin Immunotoxin: Targeted Cytotoxicity and Intracellular Trafficking Pathway

BACKGROUND: Immunotherapy is fast emerging as one of the leading modes of treatment of cancer, in combination with chemotherapy and radiation. Use of immunotoxins, proteins bearing a cell-surface receptor-specific antibody conjugated to a toxin, enhances the efficacy of cancer treatment. The toxin A...

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Detalles Bibliográficos
Autores principales: Gadadhar, Sudarshan, Karande, Anjali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589266/
https://www.ncbi.nlm.nih.gov/pubmed/23472175
http://dx.doi.org/10.1371/journal.pone.0058304