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Characterisation of P2Y(12) Receptor Responsiveness to Cysteinyl Leukotrienes
Leukotriene E(4) (LTE(4)), the most stable of the cysteinyl leukotrienes (cysLTs), binds poorly to classical type 1 and 2 cysLT receptors although in asthmatic individuals it may potently induce bronchial constriction, airway hyperresponsiveness and inflammatory cell influx to the lung. A recent stu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589271/ https://www.ncbi.nlm.nih.gov/pubmed/23472176 http://dx.doi.org/10.1371/journal.pone.0058305 |