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Characterisation of P2Y(12) Receptor Responsiveness to Cysteinyl Leukotrienes

Leukotriene E(4) (LTE(4)), the most stable of the cysteinyl leukotrienes (cysLTs), binds poorly to classical type 1 and 2 cysLT receptors although in asthmatic individuals it may potently induce bronchial constriction, airway hyperresponsiveness and inflammatory cell influx to the lung. A recent stu...

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Detalles Bibliográficos
Autores principales: Foster, Holly R., Fuerst, Elisabeth, Lee, Tak H., Cousins, Davis J., Woszczek, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589271/
https://www.ncbi.nlm.nih.gov/pubmed/23472176
http://dx.doi.org/10.1371/journal.pone.0058305