Cargando…

Characterisation of P2Y(12) Receptor Responsiveness to Cysteinyl Leukotrienes

Leukotriene E(4) (LTE(4)), the most stable of the cysteinyl leukotrienes (cysLTs), binds poorly to classical type 1 and 2 cysLT receptors although in asthmatic individuals it may potently induce bronchial constriction, airway hyperresponsiveness and inflammatory cell influx to the lung. A recent stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foster, Holly R., Fuerst, Elisabeth, Lee, Tak H., Cousins, Davis J., Woszczek, Grzegorz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589271/ https://www.ncbi.nlm.nih.gov/pubmed/23472176 http://dx.doi.org/10.1371/journal.pone.0058305

Ejemplares similares

Leukotriene E(4) is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression
por: Foster, Holly R., et al.
Publicado: (2016)

Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts
por: Kanaoka, Yoshihide, et al.
Publicado: (2014)

Cysteinyl-Leukotriene Receptors and Cellular Signals
por: Rovati, G. Enrico, et al.
Publicado: (2007)

Cysteinyl Leukotriene Pathway and Cancer
por: Tsai, Ming-Ju, et al.
Publicado: (2021)

Adipokines and Cysteinyl Leukotrienes in the Pathogenesis of Asthma
por: Coffey, Michael J., et al.
Publicado: (2015)

Montelukast: More than a Cysteinyl Leukotriene Receptor Antagonist?
por: Tintinger, Gregory R., et al.
Publicado: (2010)

Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control
por: Noronha, Letícia Paula Trajano, et al.
Publicado: (2023)

Cysteinyl Leukotriene and Systemic Inflammatory Levels in Preeclampsia
por: Guzeltas, Gokhan, et al.
Publicado: (2023)

Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
por: Tsai, Ming-Ju, et al.
Publicado: (2016)

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
por: Gusach, Anastasiia, et al.
Publicado: (2019)

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs
por: Luginina, Aleksandra, et al.
Publicado: (2019)

Cysteinyl leukotriene receptor 1 is dispensable for osteoclast differentiation and bone resorption
por: Fujita, Hirofumi, et al.
Publicado: (2022)

Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis
por: Peters-Golden, M, et al.
Publicado: (2006)

Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases
por: Gelosa, Paolo, et al.
Publicado: (2017)

Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases
por: Colazzo, Francesca, et al.
Publicado: (2017)

Cysteinyl Leukotriene Receptor-1 Antagonists as Modulators of Innate Immune Cell Function
por: Theron, A. J., et al.
Publicado: (2014)

Corrigendum: Cysteinyl Leukotriene Receptor Antagonists Decrease Cancer Risk in Asthma Patients
por: Tsai, Ming-Ju, et al.
Publicado: (2016)

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm
por: Di Gennaro, Antonio, et al.
Publicado: (2018)

Regulation of Cysteinyl Leukotriene Receptor 2 Expression—A Potential Anti-Tumor Mechanism
por: Magnusson, Cecilia, et al.
Publicado: (2011)

Structure based virtual screening of ligands to identify cysteinyl leukotriene receptor 1 antagonist
por: Bandaru, Srinivas, et al.
Publicado: (2014)

Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells
por: Koller, Andreas, et al.
Publicado: (2020)

Multifaceted Roles of Cysteinyl Leukotrienes in Eliciting Eosinophil Granule Protein Secretion
por: Baptista-dos-Reis, Renata, et al.
Publicado: (2015)

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer
por: Burke, Lorraine, et al.
Publicado: (2016)

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
por: Marin, Egor, et al.
Publicado: (2020)

Cysteinyl leukotriene type I receptor desensitization sustains Ca(2+)-dependent gene expression
por: Ng, Siaw-Wei, et al.
Publicado: (2012)

Differential Regulation of Cysteinyl Leukotriene Receptor Signaling by Protein Kinase C in Human Mast Cells
por: Kondeti, Vinay, et al.
Publicado: (2013)

Cysteinyl leukotriene receptor antagonist regulates allergic airway inflammation in an organ- and cytokine-specific manner
por: Kawano, Tetsuya, et al.
Publicado: (2014)

Cysteinyl-leukotrienes in the regulation of β(2)-adrenoceptor function: an in vitro model of asthma
por: Rovati, G Enrico, et al.
Publicado: (2006)

Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages
por: Jackson, Sarah E., et al.
Publicado: (2012)

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
por: Barrett, Nora A., et al.
Publicado: (2011)

Cysteinyl Leukotriene Signaling Aggravates Myocardial Hypoxia in Experimental Atherosclerotic Heart Disease
por: Nobili, Elena, et al.
Publicado: (2012)

Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders
por: Thompson-Souza, Glaucia A., et al.
Publicado: (2017)

Chlorine Gas, Airway Inflammation, and Cysteinyl Leukotrienes: The Neutrophil Does Not Work Alone
por: Sporn, Peter H. S.
Publicado: (2020)

Cysteinyl–leukotriene and prostaglandin pathways in bronchial versus alveolar lavage in allergic asthmatics
por: van der Burg, Nicole, et al.
Publicado: (2022)

Intracrine Cysteinyl Leukotriene Receptor–mediated Signaling of Eosinophil Vesicular Transport–mediated Interleukin-4 Secretion
por: Bandeira-Melo, Christianne, et al.
Publicado: (2002)

Regulation of dendritic cell functions against harmful respiratory pathogens by a cysteinyl leukotrienes receptor antagonist
por: Matsuse, Hiroto, et al.
Publicado: (2012)

Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer
por: Osman, Janina, et al.
Publicado: (2017)

MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication
por: Ruiz, Isaac, et al.
Publicado: (2020)

Cysteinyl Leukotriene Receptor Antagonists Associated With a Decreased Incidence of Cancer: A Retrospective Cohort Study
por: Jang, Ha Young, et al.
Publicado: (2022)

Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro
por: Chen, Yisheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6onfq5jrmkfq7up0c6nsdkdfos